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2 812 910

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IPC

C07K16/28(2006-01-01)

C07K16/00(2006-01-01)

A61K39/395(2006-01-01)

A61K45/00(2006-01-01)

C12N5/10(2006-01-01)

A61P35/00(2006-01-01)

A61P35/02(2006-01-01)

(21) (22)

Application

2020115450, 2018-10-09

(24)

Start date

2018-10-09

(22)

Actual filing date

2018-10-09

(45)

Published

2024-02-05

(72)

Inventor

Xu, LingSeung, EdwardWei, RonnieNabel, GaryYang, Zhi-YongDabdoubi, TarikCameron, BeatriceLemoine, CendrinePrades, CatherineWu, Lan

(73)

Holder

Sanofi

ANTIBODIES TO CD38 AND COMBINATIONS WITH ANTIBODIES TO CD3 AND CD28 Russian patent published in 2024 - IPC C07K16/28 C07K16/00 A61K39/395 A61K45/00 C12N5/10 A61P35/00 A61P35/02

Abstract RU 2812910 C2

FIELD: biotechnology.

SUBSTANCE: following is presented: a monospecific binding protein that binds a CD38 polypeptide, a conjugate for targeting a cytotoxic agent or tag to cells expressing CD38 on their surface, a polynucleotide encoding a monospecific binding protein, an expression vector containing the polynucleotide and a host cell. A method of producing a monospecific binding protein is also disclosed.

EFFECT: obtaining new antibodies with high affinity for HLA-G.

18 cl, 40 dwg, 27 tbl, 15 ex

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RU 2 812 910 C2

Authors

Xu, Ling

Seung, Edward

Wei, Ronnie

Nabel, Gary

Yang, Zhi-Yong

Dabdoubi, Tarik

Cameron, Beatrice

Lemoine, Cendrine

Prades, Catherine

Wu, Lan

Dates

2024-02-05—Published

2018-10-09—Filed