METHOD OF SIMULTANEOUS CYTO-HISTOBIOPSY, LOCALIZATION OF EARLY NON-PALPABLE TUMOUR AND ZONE OF RADICAL BREAST RESECTION AND NEEDLE-LOCALIZER FOR ITS IMPLEMENTATION (EMBODIMENTS) Russian patent published in 2024 - IPC A61B10/02 A61M5/32 A61B17/34 A61K35/32 A61K49/04 A61P43/00 

FIELD: medicine; oncology; surgery.

SUBSTANCE: anaesthesia of the area of interest, puncture, sampling of material and localization of the tumour are carried out under ultrasound or X-ray control. The needle localizer from the kit for cytobiopsy, localization of tumours and zones of radical resection of the mammary gland according to claim 2, is inserted into the tumour before the inner cut of the needle. A biopsy stylet drill is screwed into the tumour. Then a localizer needle is screwed onto the stylet-drill and the stylet-drill with the biopsy sample is removed. The contents of the puncture channel are aspirated with a syringe. Then a cytostatic agent is injected into the channel, a marker is inserted into the localizer needle and, using a mandrel, it is pushed into the centre of the tumour node. Then the localizer needle is pulled so that its end extends 1–1.5 cm from the tumour and is directed to the lateral peritumoral zone, where the first marker is installed at a distance of 1 cm from the edge of the tumour using a mandrel. After this, the localizer needle is pulled up again and its end is directed to the upper pole of the tumour, where a second marker is installed at a distance of 1 cm from its edge with a mandrel, then the localizer needle is pulled up again and its end is directed to the medial zone of the tumour, where 1 cm from the edges of the mandrel set the third marker. After this, the localizer needle is pulled up and its end is directed to the lower pole of the tumour, and a fourth marker is installed at a distance of 1 cm from its edge using a mandrel. Then, a marker-rod is inserted into the localizer needle, which is bone meal, formed as a rod in the lumen of the subclavian catheter with a length corresponding to the length of the puncture channel, and the marker is pushed through a mandrel so that its inner end reaches the edge of the tumour, and the outer end is located subcutaneously. Kit for cyto-histobiopsy, localization of tumours and areas of radical resection of the mammary gland containing a localizer needle, equipped with a V-shaped two-way connector, a mandrel and a biopsy stylet drill and an interstitial marker in the form of bone meal, diluted in a cytostatic agent in the form of a paste, coloured in blue colour, or bone meal, formed in the form of a rod in the lumen of the subclavian catheter.

EFFECT: visualization of non-palpable and palpable neoplasms and areas of radical resection of the mammary gland with simultaneous cyto-histobiopsy, antiblastics of the puncture canal and haemostasis.

2 cl, 4 dwg, 2 ex