FIELD: medicine.
SUBSTANCE: group of inventions relates to the treatment of haematological malignant diseases. Combination for treating a hyperproliferative disorder contains a compound of formula (I) or a pharmaceutically acceptable salt thereof, a BCL2 inhibitor selected from venetoclax, ABT-737 and pharmaceutically acceptable salts thereof.
Also disclosed are a pharmaceutical composition, a kit, methods of treating a hyperproliferative disorder, using a combination for treating a hyperproliferative disorder and for preparing a drug.
EFFECT: group of inventions provides achieving a synergetic effect on cancer cell inhibition.
40 cl, 22 dwg, 4 tbl, 2 ex
Title | Year | Author | Number |
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|
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TREATING MALIGNANT TUMOURS USING MODULATORS OF PI3-KINASE ISOFORMS | 2013 |
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COMBINATION THERAPIES FOR THE TREATMENT OF CANCER | 2016 |
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RU2759963C2 |
Authors
Dates
2024-04-02—Published
2017-03-13—Filed