HARDWARE-ACCELERATED GENERATION OF K-DIMENSIONAL GRAPH Russian patent published in 2024 - IPC G16B30/20 G16B20/20 

Abstract RU 2817560 C1

FIELD: computer engineering.

SUBSTANCE: invention relates to methods and systems for hardware-accelerated generation of K-dimensional graphs representing multiple sequencing reads for analysis of variant recognition. In one aspect, the method involves steps for obtaining a first set of nucleotide sequences generated by a nucleic acid sequencer, constructing a K-dimensional graph using the obtained first set of nucleotide sequences and using a plurality of non-pipelined hardware logic units of the programmable logic device, and periodic updating, by means of the data management device, of the graphical representation for the K-dimensional graph after performing one or more operations by each hardware logic unit.

EFFECT: faster generation of a K-dimensional graph, which leads to faster genome analysis as a whole.

34 cl, 5 dwg

Similar patents RU2817560C1

Title Year Author Number
FLEXIBLE SEED EXTENSION FOR HASH TABLE-BASED GENOMIC MAPPING 2020
  • Ruehle, Michael
RU2796915C1
FAST DETECTION OF GENE FUSIONS 2020
  • Deshpande, Viraj
  • Shlezinger, Jokhann Feliks Vilgelm
  • Truong, Shon
  • Roddi, Dzhon Kuper
  • Ryule, Majkl
  • Katru, Severin
  • Mekho, Rami
RU2818363C1
GENOMIC INFRASTRUCTURE FOR LOCAL AND CLOUD PROCESSING AND ANALYSIS OF DNA AND RNA 2017
  • Van Rojn, Piter
  • Makmillen, Robert Dzh.
  • Ryule, Majkl
  • Mekho, Rami
RU2804029C2
GENOMIC INFRASTRUCTURE FOR LOCAL AND CLOUD PROCESSING AND ANALYSIS OF DNA AND RNA 2017
  • Van Rojn, Piter
  • Makmillen, Robert Dzh.
  • Ryule, Majkl
  • Mekho, Rami
RU2761066C2
SEQUENCE GRAPH-BASED TOOL FOR DETERMINING VARIATION IN SHORT TANDEM REPEAT AREAS 2020
  • Dolzhenko, Egor
  • Eberle, Michael A.
RU2799654C2
SEQUENCE GRAPH TOOL FOR DETERMINING VARIATIONS IN REGIONS OF SHORT TANDEM REPEATS 2020
  • Dolzhenko, Egor
  • Eberle, Michael A.
RU2825664C2
PHASING CORRECTION 2018
  • Langlua, Robert
  • Belits, Pol
RU2805952C2
PHASING CORRECTION 2018
  • Langlua, Robert
  • Belits, Pol
RU2765996C2
METHOD AND SYSTEM FOR DETERMINING NUCLEOTIDE SEQUENCE IN GIVEN REGION OF FOETAL GENOME 2012
  • Chen Shenpej
  • Ge Khuejtszyuan
  • Li Khuchao
  • I Shan
  • Van Tszyan
  • Van Tszyun
  • Yan Khuanmin
  • Chzhan Syutsin
RU2597981C2
METHOD OF COMPRESSING GENOME SEQUENCE DATA 2020
  • Rizk, Gijom Aleksandr Paskal
RU2815860C1

RU 2 817 560 C1

Authors

Ryule, Majkl

Dates

2024-04-16Published

2021-04-07Filed