BACILLUS SUBTILIS-BASED LYOPHILISATE FOR ANTI-TUMOUR IMMUNITY REPROGRAMMING Russian patent published in 2024 - IPC C12N1/20 A61K35/742 C12R1/125 

Abstract RU 2821073 C1

FIELD: biotechnology.

SUBSTANCE: what is presented is a lyophilisate based on Bacillus subtilis 2335 pBMB105 for reprogramming immunity in the anti-tumour direction with the following composition of components, g: biomass of Bacillus subtilis 2335 pBMB105 bacteria strain in amount of 0.0020, which corresponds to 1⋅109 living microbial cells; filler: gelatine 0.0060, sodium chloride 0.0017, sucrose 0.0200.

EFFECT: invention provides a wider range of agents characterized by pronounced immunomodulatory activity for use in complex therapy of oncological diseases.

1 cl, 4 tbl, 4 ex

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RU 2 821 073 C1

Authors

Kajdash Olga Aleksandrovna

Ufandeev Aleksandr Anatolevich

Bujko Evgenij Evgenevich

Perina Ekaterina Aleksandrovna

Khmelevskaya Ekaterina Sergeevna

Efimova Lina Viktorovna

Pershina Aleksandra Gennadevna

Ivanov Vladimir Vladimirovich

Udut Elena Vladimirovna

Litvyakov Nikolaj Vasilevich

Cherdyntseva Nadezhda Viktorovna

Belyavskaya Valentina Aleksandrovna

Kzhyshkovska Yuliya Georgievna

Dates

2024-06-17Published

2023-12-15Filed