FIELD: medicine, microbiology. SUBSTANCE: biopreparation has an antibiotic-resistant antagonistically active strain Bacillus subtilis 3H (GISK N 248) as a base and a filling agent. Filling agent has 5% lactose or 8% sucrose-gelatin mixture. Preparation can be used for correction of gastroenteric tract microflora at dysbacteriosis, enzymatic deficiency of digestion organs, suppurative infections, alimentary allergy, for treatment of surgery infection of soft tissues, prophylaxis of surgery infection at traumas and surgery operations. EFFECT: high antagonistic activity with respect to broad spectrum of pathogenic and opportunistic microorganisms and resistance to many antibiotics. 3 tbl, 3 ex
