FIELD: chemistry.
SUBSTANCE: invention relates to a compound of Formula I
where R1 is an alkyl of formula -(CH2)n-CH3, where n is an integer selected from 6, 7, 8, 9, 10, 11 or 12; or R1 is 
as well as to abiraterone decanoate of formula:
as well as to pharmaceutical compositions based thereon, methods treating a sex hormone-dependent benign or malignant disease.
EFFECT: novel prolonged-action abiraterone prodrugs are obtained, which can be used for treating a sex hormone-dependent benign or malignant disease.
33 cl, 8 ex, 13 tbl, 17 dwg
| Title |
Year |
Author |
Number |
| DELAYED RELEASE BUPRENORPHINE PREPARATIONS |
2017 |
- Lin, Tong-Ho
- Wen, Yung-Shun
- Liang, Jui-Wei
|
RU2747306C2 |
| PHORBOL ESTER COMPOSITIONS AND METHODS OF USING THEM FOR TREATING OR REDUCING DURATION OF CYTOPENIA |
2015 |
|
RU2730998C2 |
| PHARMACEUTICAL COMPOSITIONS FOR PROLONGED RELEASE OF SEBACOYL-DINALBUPHINE ESTER |
2016 |
- Li Chan-Tszyun
- Chou Dejvid Chi-Kuan
- Khuan Tszin-Din
- Tsaj Shin Mladshij
- Ko Shu-Ven
- Ten Yuj-En
|
RU2718900C2 |
| COMBINATION THERAPY |
2017 |
|
RU2754507C2 |
| METHODS FOR USING A PHENOXYPROPYLAMINE COMPOUND FOR THE TREATMENT OF PAIN |
2019 |
- Luthringer, Remy
- Noel, Nadine
- Saoud, Jay
|
RU2797615C2 |
| COMBINATION THERAPY WITH TETRACYCLIC QUINOLONE ANALOGUES FOR TREATMENT OF CANCER |
2016 |
|
RU2786570C2 |
| COMBINED THERAPY WITH TETRACYCLIC QUINOLONE ANALOGUES FOR CANCER TREATMENT |
2016 |
|
RU2752506C2 |
| EXTENDED-RELEASE INJECTION COMPOSITION OF NALTREXONE |
2019 |
- Lin, Ton-Kho
- Ven, Yun-Shun
- Lyu, In-Tin
- U, Chzhi-Zhun
|
RU2806817C2 |
| METHOD OF TREATMENT BY APPLICATION OF COMBINED THERAPY |
2010 |
- Armstrong Robert K.
- Belli Barbara A.
|
RU2543348C2 |
| FULVESTRANT COMPOSITIONS |
2018 |
- Anshakova Olga Aleksandrovna
- Iakovlev Aleksandr Olegovich
|
RU2684330C1 |
