FIELD: biotechnology; medicine.
SUBSTANCE: present invention to a murine monoclonal antibody capable of binding to rabies viruses or viruses related to rabies viruses, and neutralize these viruses, as well as to a cocktail of at least two monoclonal antibodies having said properties. Present invention also relates to a combination of a murine monoclonal antibody or a cocktail of at least two monoclonal antibodies and rabies vaccines for use in post-exposure prophylaxis (PEP) of rabies virus or rabies virus related viruses.
EFFECT: cocktail can neutralize a virus originating from such species as bats, dogs, cows, mongooses, skunks and wolves, and thus it can be used for treating a potentially infected patient.
10 cl, 1 dwg, 7 tbl, 7 ex
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Authors
Dates
2024-07-05—Published
2019-10-24—Filed