FIELD: medicine.
SUBSTANCE: present invention relates to a method of killing cancer cells using a combination of an HDAC inhibitor and an anti-PD1 antibody or an anti-PD-L1 antibody.
EFFECT: present invention provides an effective effect on increasing the survival rate of animals suffering from cancer, tumours, disorders caused by tumours, and neoplastic diseases, inhibition of proliferative cell growth associated with neoplasms, or neoplastic degeneration.
16 cl, 2 dwg, 1 tbl, 1 ex
| Title |
Year |
Author |
Number |
| COMBINATION OF HDAC INHIBITOR AND ANTI-PD-1 ANTIBODY FOR TREATMENT OF CANCER |
2016 |
- Ordentlich, Peter
- Goodenow, Robert
|
RU2796903C2 |
| PHARMACEUTICAL COMPOSITION CONTAINING ALKYLCARBAMOYLNAPHTHALENYLOXY-OCTOYLHYDROXYAMIDE PHOSPHATE, ALKYLCARBAMOYLNAPHTHALENYLOXYOXTENOYLHYDROXYAMIDE TARTRATE OR COMBINATION THEREOF, AND METHOD FOR PRODUCTION THEREOF |
2019 |
- Chkho, Che Peun
- Chkho, Choon Myun
|
RU2816889C2 |
| PHARMACEUTICALLY ACCEPTABLE SALT OF ALKYLCARBAMOYLNAPHTHALENYLOXYOXYCTENOYL HYDROXY AMIDE OR DERIVATIVE THEREOF AND METHOD FOR PRODUCTION THEREOF |
2018 |
- Chkho, Che Peun
- Chun, En Kho
- Chkho, Choon Myun
|
RU2736216C1 |
| COMBINATION OF TASQUINIMOD OR ITS PHARMACEUTICALLY ACCEPTABLE SALT AND PD-1 AND/OR PD-L1 INHIBITOR FOR USE AS A MEDICINAL AGENT |
2016 |
- Soares Khose Amauri
- Shetaj Erik
- Nekl Dzhessika
- Shmidlen Faben
|
RU2742373C2 |
| THIOCARBAMATE DERIVATIVES AS A2A INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND COMBINATIONS THEREOF WITH ANTICANCER AGENTS |
2019 |
- Crosignani, Stefano
- Dickinson, Paul
- De Matas, Marcel
- Houthuys, Erica Joke Katelijne Heleen
- Marillier, Reece Gerrad
- Martinoli, Chiara
- De Henau, Olivier
- Driessens, Gregory
|
RU2824502C2 |
| TREATMENT OF CANCER, USING ANTIBODY TO SEMAPHORIN 4D IN COMBINATION WITH EPIGENETIC MODULATING AGENT |
2018 |
- Evans, Elizabet
- Smit, Ernest S.
- Zauderer, Moris
|
RU2783535C2 |
| COMBINATIONS OF DUAL MODULATORS IRS/STAT3 AND ANTIBODIES TO PD-1/PD-L1 FOR CANCER TREATMENT |
2017 |
- Reuveni, Khadas
- Kupershmidt, Lana
- Khaviv, Itskhak
|
RU2796275C2 |
| COMBINED TREATMENT METHODS USING ALK INHIBITORS |
2015 |
- Lebvol Devid
- Peters Malte
- Li Nansin
- Lau I Yan
- Skott Dzheffri
|
RU2718914C2 |
| COMPOSITIONS CONTAINING ANTI-SEAMS 1 AND ANTI-PD ANTIBODIES FOR CANCER THERAPY |
2014 |
- Ben-Moshe Tekhila
- Sapir Yar
- Mendel Ilana
- Mejlin Edna
|
RU2697522C1 |
| REDUCTION OF TUMOR MASS BY INJECTING CCR1 ANTAGONISTS IN COMBINATION WITH PD-1 INHIBITORS OR PD-L1 INHIBITORS |
2017 |
- Sharo Izrael
- Chon Khejyun
- Shall Tomas Dzh.
- Chzhan Penli
|
RU2745195C2 |
