KETAMINE PAMOATE AND USE THEREOF Russian patent published in 2024 - IPC C07C225/20 A61K31/135 C07C65/11 A61P25/24 

Abstract RU 2825336 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a ketamine pamoate salt having a stoichiometric ratio of ketamine to pamoate of 2:1, which is a pamoate salt of R, S-ketamine, represented by structural formula (I), a pamoate salt of S-ketamine, represented by structural formula (II), or a pamoate salt of R-ketamine, presented below by structural formula (III). Invention relates to method of treating a disease of the central nervous system (CNS), comprising administering to a subject in need thereof an effective amount of a pharmaceutical composition, where the pharmaceutical composition contains a ketamine pamoate salt according to invention, pharmaceutically acceptable excipient. Invention also relates to anaesthesia of a subject in need thereof, comprising administering to the subject an effective amount of a pharmaceutical composition, where the pharmaceutical composition contains a ketamine pamoate salt according to the invention and a pharmaceutically acceptable excipient thereof.

EFFECT: ketamine pamoate salt for pharmaceutical use.

11 cl, 14 dwg, 8 tbl, 5 ex

(I), (II),

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RU 2 825 336 C2

Authors

Lin, Ton-Kho

Ven, Yun-Shun

Chen, Chia-Syan

Chan, Vej-Tszyuj

Dates

2024-08-26Published

2020-01-10Filed