CRYSTALS OF CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF Russian patent published in 2020 - IPC C07D401/06 A61K31/454 A61P21/00 A61P25/04 

Abstract RU 2719384 C1

FIELD: chemistry.

SUBSTANCE: invention relates to organic chemistry and specifically to crystalline form of (S)-1-(4-(dimethylamino)piperidin-1-yl)-3-hydroxy-3-(1-methyl-1H-imidazol-2-yl)propan-1-one, on a powder X-ray diffraction pattern of which there are peaks at diffraction angles of 2θ(°) 15.3 ± 0.2, 16.0 ± 0.2, 19.0 ± 0.2, 21.8 ± 0.2 and 23.0 ± 0.2. Invention also relates to a medicinal analgesic and therapeutic agent based thereon, as well as to a pharmaceutical composition based thereon.

EFFECT: technical result is obtaining a compound in crystalline form having analgesic action.

6 cl, 6 dwg, 7 tbl, 11 ex

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RU 2 719 384 C1

Authors

Takahashi Hirozumi

Baba Yoko

Morita Yasuhiro

Iseki Katsuhiko

Izumimoto Naoki

Dates

2020-04-17Published

2017-08-25Filed