PEPTIDE DRUG Russian patent published in 2024 - IPC A61K38/10 C07K7/08 A61P29/00

Abstract RU 2827765 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, in particular to biologically active peptides having anti-inflammatory properties due to the ability to inhibit migration of monocytic blood cells, stimulated by protein MCP-1 (monocyte chemoattractant protein-1). Declared is 13-member peptide of formula KWVQDSINYLNKK-Y, where Y=NH₂, having anti-inflammatory additional antioxidant and antiaggregatory properties, or its pharmaceutically acceptable salts.

EFFECT: said compounds can be used in treating diseases associated with migration of monocytes and requiring prolonged therapy, such as atherosclerosis, psoriasis, rheumatoid arthritis, dermatitis, and so forth.

1 cl, 1 tbl, 3 ex

Similar patents RU2827765C2

Title	Year	Author	Number
METHOD OF ASSESSING THE EFFICIENCY OF ANTI-CLEGGANT MEDICINAL PRODUCT IN WHOLE PERIPHERAL BLOOD SAMPLES	2022	Chepanov Sergej Vladimirovich Pavlov Oleg Vladimirovich Peretyatko Ilya Sergeevich Shengeliya Margarita Olegovna Ruleva Anna Vladimirovna Mozgovaya Elena Vitalevna Selkov Sergej Alekseevich	RU2800671C1
RGD-LIKE PEPTIDES	2009	Belushkina Natal'Ja Nikolaevna Kovtun Anatolij Leonidovich Kosenko Sergej Ivanovich Makhlaj Aleksandr Aleksandrovich Pavlova Ljudmila Anatol'Evna Kislova Julija Vladimirovna Ul'Janov Andrej Mikhajlovich Kulygina Irina Vladimirovna Ignatova Anastasija Igorevna	RU2396271C1
PEPTIDE FOR INHIBITING FRACTALKINE-STIMULATED MIGRATION OF MONOCYTIC CELLS	2011	Az'Muko Andrej Andreevich Aref'Eva Tat'Jana Igorevna Bespalova Zhanna Dmitrievna Krasnikova Tat'Jana Leonidovna Kukhtina Nadezhda Borisovna Molokoedov Aleksandr Sergeevich Pal'Keeva Marina Evgen'Evna Ruleva Natal'Ja Jur'Evna Sidorova Marija Vladimirovna Sokolov Vladimir Olegovich	RU2461565C1
THROMBOCYTE AGGREGATION-INHIBITING HETEROMERIC PEPTIDES BASED ON IMIDAZO[4,5-e]BENZO[1,2-c;3,4-c']DIFUROXANE	2014	Alekseev Aleksej Anatol'Evich Brylev Maksim Igorevich Korolev Vjacheslav Leonidovich Lotorev Dmitrij Sergeevich Lizunov Anton Jur'Evich Pavlova Ljudmila Anatol'Evna Belushkina Natal'Ja Nikolaevna	RU2550223C1
PEPTIDE ELICITING CAPACITY TO INHIBIT MIGRATION OF MONOCYTIC CELLS STIMULATED BY PROTEIN MCP-1	2003	Chazov E.I. Sidorova M.V. Molokoedov A.S. Aref'Eva T.I. Kukhtina N.B. Krasnikova T.L. Bespalova Zh.D. Bushuev V.N.	RU2260598C2
THROMBOCYTE AGGREGATION-INHIBITING N-CARB(GLUTAMINYL)OXYMETHYLIMIDAZO[4,5-E]BENZO[1,2-C;3,4-C']DIFUROXANE	2012	Alekseev Aleksej Anatol'Evich Brylev Maksim Igorevich Korolev Vjacheslav Leonidovich Lotorev Dmitrij Sergeevich Batuev Evgenij Andreevich Pavlova Ljudmila Anatol'Evna Belushkina Natal'Ja Nikolaevna	RU2502739C9
METHOD FOR FUNCTIONAL AND QUANTITATIVE EVALUATION OF PLATELET-MONOCYTIC COMPLEXES IN WHOLE PERIPHERAL BLOOD SAMPLES	2020	Chepanov Sergej Vladimirovich Pavlov Oleg Vladimirovich Selyutin Aleksandr Vasilevich Orlova Ekaterina Sergeevna Kornyushina Ekaterina Amirovna Selkov Sergej Alekseevich	RU2762820C1
THROMBOCYTE AGGREGATION-INHIBITING N-CARB(ARGINYL)OXYMETHYLIMIDAZO[4,5-e]BENZO[1,2-c;3,4-c']DIFUROXANE	2014	Alekseev Aleksej Anatol'Evich Brylev Maksim Igorevich Korolev Vjacheslav Leonidovich Lotorev Dmitrij Sergeevich Batuev Evgenij Andreevich Pavlova Ljudmila Anatol'Evna Belushkina Natal'Ja Nikolaevna	RU2549355C1
METHOD FOR THE PRODUCTION OF PLATELETS BY A METHOD FOR ROTATIONAL MIXING OF THE CULTURE	2016	Shigemori, Tomohiro Okamoto, Haruki	RU2756000C2
PHARMACEUTICAL COMPOSITION WITH PROLONGED RELEASE OF DODECAPEPTIDE INGRAMON	2022	Arefeva Tatyana Igorevna Sidorova Mariya Vladimirovna Ovchinnikov Mikhail Vladimirovich Esipov Dmitrij Stanislavovich Marmij Natalya Vladimirovna Radyukhina Natalya Vladimirovna Molokoedov Aleksandr Sergeevich Avdeev Dmitrij Viktorovich Filatova Anastasiya Yurevna Ruleva Natalya Yurevna	RU2793124C1

RU 2 827 765 C2

Authors

Savelev Sergej Aleksandrovich

Dates

2024-10-01—Published

2022-06-02—Filed