COMPOSITIONS OF ANTI-CD6 ANTIBODIES AND METHODS OF TREATING AND REDUCING NEGATIVE CONSEQUENCES OF CORONAVIRUS, INCLUDING COVID-19 Russian patent published in 2024 - IPC A61K39/395 C07K16/28 A61P31/04 A61P31/14 

Abstract RU 2828013 C1

FIELD: biotechnology.

SUBSTANCE: disclosed are the use of a non- depleting anti-CD6 antibody that specifically binds to domain 1 of CD6, for the treatment of an infectious disease that leads to a cytokine storm or cytokine release syndrome, for the treatment of an infectious disease caused by a coronavirus, which leads to a cytokine storm or a cytokine release syndrome, and for the treatment of COVID-19. Also disclosed is a kit for treating a subject against COVID-19.

EFFECT: inventions extend the range of products for treating and reducing the negative consequences caused by infectious agents, especially coronaviruses, wherein said negative consequences include triggering a cytokine storm or cytokine release syndrome.

17 cl, 9 dwg, 5 tbl, 10 ex

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RU 2 828 013 C1

Authors

Nair, Pradip

Kasimiro, Khose Enrike Montero

Mazumdar Shav, Kiran

Bugani, Usha

Atale, Sandip Nilkant

Ramakrishnan, Melarkod Subbaraman

Krombet Ramos, Taniya

Leon Monson, Kalet

Ramos Susarte, Majra

Dates

2024-10-07Published

2021-04-03Filed