FIELD: biotechnology.
SUBSTANCE: invention relates to the use of a chimeric antigen receptor (CAR) therapy for CD19, containing a population of immune effector cells expressing CAR for CD19, for the treatment of cancer in a subject in combination with a PD–1 inhibitor. Also a method of treating a subject having cancer, comprising administering to the subject a CD19 CAR therapy and a PD-1 inhibitor is disclosed.
EFFECT: invention is effective for the treatment of cancer.
95 cl, 14 dwg, 8 tbl, 16 ex
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