SELF-ASSEMBLED PEPTIDES IN PREVENTION AND TREATMENT OF CAVITIES ACCOMPANIED BY FORMATION OF CAVITIES Russian patent published in 2024 - IPC A61K6/20 A61K6/69 A61K6/889 

FIELD: medicine.

SUBSTANCE: group of inventions relates to the field of agents for preventing and treating caries, particularly minimally invasive or non-invasive caries treatment, and concerns a composition and a kit, as well as use thereof. Disclosed composition and kit contain: a) a self-assembled peptide representing P11-4, having SEQ ID NO: 6, and b) a dental substance; wherein the kit contains the above components in separate form. Dental substance used in the composition is: dental sealant selected from the group of glass ionomer cements and polymer-modified glass ionomer cements; or fluorine lacquer containing ethyl alcohol as a solvent in combination with rosin or shellac base; set includes a dental sealant based on glass ionomer cement, selected from a group comprising glass ionomer cements and polymer-modified glass ionomer cements. Also disclosed is the use of said composition or kit in preventing secondary caries after unsuccessful use of a dental substance in treating a cavity-forming carious lesion, as well as in a protective coating of the pulp.

EFFECT: use of the self-assembled peptide P11-4 in the above composition and kit provides the prevention of secondary caries after the unsuccessful use of the dental substance used in the treatment of caries accompanied by cavity formation, especially in case of violation of boundary between restoration made of said dental substance, and tooth, and, besides, it is effective for protective coating of pulp.

15 cl, 7 dwg, 2 tbl, 7 ex