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2 829 511

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IPC

G01N33/564(2006-01-01)

G01N33/48(2006-01-01)

G01N33/567(2006-01-01)

G01N33/573(2006-01-01)

(21) (22)

Application

2023133329, 2023-12-15

(24)

Start date

2023-12-15

(22)

Actual filing date

2023-12-15

(45)

Published

2024-10-31

(72)

Inventor

Adamyan Lejla VladimirovnaMenzhinskaya Irina VladimirovnaMakiyan Zograb NikolaevichKozachenko Irena FeliksovnaAntonova Alena AlekseevnaTonoyan Narine MarzpetunovnaArakelyan Alek SejranovichKrechetova Lyubov ValentinovnaSukhikh Gennadij Tikhonovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Meditsinskij Issledovatelskij Tsentr Akusherstva, Ginekologii I Perinatologii Imeni Akademika V.I. Kulakova" Ministerstva Zdravookhraneniya Rossijskoj Federatsii

METHOD FOR LABORATORY DIAGNOSIS OF PREMATURE OVARIAN FAILURE BY DETERMINATION OF AUTOANTIBODIES TO STEROIDOGENIC ENZYMES OF CYTOCHROME P450 IN BLOOD SERUM (PLASMA) BY ENZYME IMMUNOASSAY Russian patent published in 2024 - IPC G01N33/564 G01N33/48 G01N33/567 G01N33/573

Abstract RU 2829511 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, particularly to a method for laboratory diagnosis of premature ovarian failure. Said method is based on determination of autoantibodies to steroidogenic enzymes of cytochrome P450 in blood serum and plasma by enzyme immunoassay.

EFFECT: invention provides a method for laboratory diagnosis of premature ovarian failure by determining autoantibodies to steroidogenic human cytochrome P450 enzymes, namely to CYP21A2, CYP11A1 and CYP19A1, in human blood serum by enzyme immunoassay.

1 cl, 9 tbl, 4 ex

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RU 2 829 511 C1

Authors

Adamyan Lejla Vladimirovna

Menzhinskaya Irina Vladimirovna

Makiyan Zograb Nikolaevich

Kozachenko Irena Feliksovna

Antonova Alena Alekseevna

Tonoyan Narine Marzpetunovna

Arakelyan Alek Sejranovich

Krechetova Lyubov Valentinovna

Sukhikh Gennadij Tikhonovich

Dates

2024-10-31—Published

2023-12-15—Filed