ENTERAL DIABETIC MIXTURE CONTAINING METABIOTIC COMPLEX AND β-GLUCANS, FOR TREATMENT OF NUTRITIONAL DEFICIENCY IN CRITICALLY ILL PATIENTS Russian patent published in 2025 - IPC A23L33/105 A23L33/115 A23L33/15 A23L33/19 A23L33/24 A61P3/10 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to an enteral diabetic mixture for treating nutritional deficiency in critically ill patients. Enteral diabetic mixture containing a metabiotic complex and β-glucans, for the treatment of nutritional deficiency in critically ill patients, containing: defatted milk, milk with fat weight fraction – 3.8%, milk protein concentrate, sunflower oil, camelina oil, fermented oat fibre, microcrystalline cellulose, vitamin-mineral premix, fructose, metabiotic complex, maltodextrin, water, wherein said elements of the mixture are contained in the following ratio of components by weight: defatted milk 40.45%; milk with fat weight fraction – 3.8% 43.83%; milk protein concentrate 1.65 %; sunflower oil 0.85%; camelina oil 0.84%; fermented oat fibre 1.50%; microcrystalline cellulose 0.60%; vitamin-mineral premix 0.70%; fructose 1.60%; metabiotic complex 0.10%; maltodextrin 5.08%; water 2.80%; wherein fermented oat fibre contains, β-glucans in an amount of components of not less than 0.033% of the total weight of the enteric mixture; the metabiotic complex contains: lysates of bacterial strains: Streptococcus thermophilus B-2011, Bifidobacterium bifidum AC-1579, Bifidobacterium adolescentis AC-1245, Bifidobacterium animalis AC-1248, Bifidobacterium longum AC-1243, Bifidobacterium breve AC-1570, Bifidobacterium infantis AC-1732, Lactobacillus acidophilus B-12024, Lactobacillus acidophilus B-1880, Lactobacillus plantarum B-11007, Lactobacillus plantarum B-11264, Lactobacillus delbrueckii subsp.bulgaricus B-2746, Lactobacillus salivarius B-2214, Lactobacillus salivarius B-2216, Lactobacillus rhamnosus B-8238, Lactobacillus rhamnosus B-6778, Lactobacillus helveticus B-2370, Lactobacillus helveticus B-2371, concentrate for the non-alcoholic beverage Cambiochaya, maltodextrin, gum arabic, food lactic acid, wherein the above elements of the metabiotic complex are contained in the following weight ratio: Bifidobacteriumbifidum AC-1579 0.00633-0.00667%; Bifidobacteriumadolescentis AC-1245 0.00633-0.00667%; Bifidobacteriumanimalis AC-1248 0.00633-0.00667%; Bifidobacteriumlongum AC-1243 0.00633-0.00667%; Bifidobacterium breve AC-1570 0.00633-0.00666%; Bifidobacterium infantis AC-1732 0.00633-0.00666%; Lactobacillus acidophilus B-12024 0.000382-0.00040%; Lactobacillus acidophilus B-1880 0.000382-0.00040%; Lactobacillus plantarum B-11007 0.000382-0.00040%; Lactobacillus plantarum B-11264 0.000382-0.00040%; Lactobacillus delbrueckiisubsp.bulgaricus B-2746 0.000382-0.00040%; Lactobacillus salivarius B-2214 0.000382-0.00040%; Lactobacillus salivarius B-2216 0.000382-0.00040%; Lactobacillus rhamnosus B-8238 0.000382-0.00040%; Lactobacillus rhamnosus B-6778 0.000382-0.00040%; Lactobacillus helveticus B-2370 0.000381-0.00040%; Lactobacillus helveticus B-2371 0.000381-0.00040%; Streptococcusthermophilus B-2011 0.01950-0.02050%; maltodextrin 0.00800-0.00826%; concentrate for non-alcoholic beverage Cambio tea 0.01900-0.01930%; gum arabic 0.00728-0.00752%; lactic acid 0.00202-0.00204%; vitamin-mineral premix contains: sodium citrate, potassium citrate, magnesium dicitrate, iron pyrophosphate, choline bitartrate, sodium chloride, sodium ascorbate, tocopherol acetate, zinc citrate, nicotinamide, manganese asparaginate, retinol acetate, copper asparaginate, beta-carotene, calcium pantothenate, cholecalciferol, pyridoxine hydrochloride, thiamine mononitrate, sodium molybdate, phylloquinone, riboflavin, chromium picolinate, folic acid, potassium iodate, sodium selenite, D-biotin, maltodextrin, wherein said vitamin-mineral premix elements are contained in the following ratio of components by weight: sodium citrate 0.221%; potassium citrate 0.155%; magnesium dicitrate 0.088%; iron pyrophosphate 0.052%; choline bitartrate 0.051%; sodium chloride 0.046%; sodium ascorbate 0.016%; tocopherol acetate 0.006%; zinc citrate 0.004%; nicotinamide 0.002%; manganese asparaginate 0.001%; retinol acetate 0.0009%; copper asparaginate 0.0008%; beta-carotene 0.0005%; calcium pantothenate 0.0005%; cholecalciferol 0.0004%; pyridoxine hydrochloride 0.0003%; thiamine mononitrate 0.0003 %; sodium molybdate 0.0002%; phylloquinone 0.0002%; riboflavin 0.0001%; chromium picolinate 0.00006%; folic acid 0.00003%; potassium iodate 0.00001%; sodium selenite 0.00001%; D-biotin 0.000005%; maltodextrin 0.053685%.

EFFECT: above described enteral mixture increases efficiency of treatment of intestinal dysbiosis, nutritional and multiple organ failure in patients in acute and chronic critical conditions.

1 cl, 1 dwg, 4 tbl, 3 ex