METHOD FOR PREPARING A THERAPEUTIC TOOTHPASTE FOR PATIENTS WITH HAEMOPHILIA Russian patent published in 2025 - IPC A61K8/18 A61K8/34 A61K8/44 A61K8/66 A61K8/81 A61K8/9789 A61K31/195 A61K36/537 A61K38/48 A61P1/02 A61Q11/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to pharmacy, and can be used in dentistry in the integrated treatment of dental diseases in paediatric and adult patients suffering haemophilia. According to the proposed method of producing a therapeutic toothpaste for patients with haemophilia, the calculated amount of carbomer-980 is uniformly applied on the surface of purified water, left until the polymer is completely dissolved, sodium hydroxide solution is added to the required gel-like consistency (pH=6-8), after which tranexamic acid, sage extract and bromelain are dissolved in 20 ml of purified water and mixed with obtained gel base, Then one gradually adds food grade blue lustrous e133 in water and glycerine with propylene glycol, mint essential oil, 70 % non-crystallisable sorbitol solution, with the following ratio of components, g: carbomer-980 0.3-0.6, glycerol 5.0-10.0, propylene glycol 5.0-10.0, sodium hydroxide – to pH=6-8, sorbitol 70 % non-crystallisable solution 1.0-5.0, mint essential oil 0.1 ml, tranexamic acid 0.01, bromelain 0.05, sage dry extract 0.5, Brilliant blue food colourant (e133) 0.05, purified water – up to 100.0.

EFFECT: expansion of the range of complex products of individual oral hygiene for patients with haemophilia of children and adults due to use of therapeutic-and-prophylactic toothpaste, having anti-inflammatory, anti-caries, antimicrobial effects, which helps to reduce gingival haemorrhage and prevents formation of dental deposit in case of individual and professional use.

1 cl, 1 ex, 4 dwg