FIELD: chemistry.
SUBSTANCE: invention relates to compounds of formula ,
where R1 represents a carboxyl group or 3-methyl-1,2,4-oxadiazol-5-yl as a substitute: , R2 is an alkyl (C1-C5), cyclopropylmethyl, propargyl, 2,2,2-trifluoroethyl or ether substitute from the row:
, R3 represents: H, CH3.
EFFECT: novel low-molecular glucagon-like peptide-1 (GLP-1) receptor agonists are synthesized; the invention enables to expand the range of low-molecular GLP-1 receptor agonists.
19 cl, 9 dwg, 3 tbl, 82 ex
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Authors
Dates
2025-04-14—Published
2024-12-13—Filed