FIELD: chemistry.
SUBSTANCE: invention relates to a compound represented by the formula (1) or a pharmaceutically acceptable salt thereof. In the formula (1) R1 is C1-6 alkyl group; R2 and R3 are the same or different from each other and each represents a hydrogen atom or a C1-6 alkyl group; X2, X3 and X4 are the same or different from each other and each represents a hydrogen atom or a halogen atom; and X5 represents a hydrogen atom or -P(=O)(OH)2. Invention also relates to compounds selected from the group, to individual compounds and to a pharmaceutical composition.
.
EFFECT: new compounds of formula (1) having the properties of a Wnt signaling inhibitor have been obtained.
17 cl, 3 dwg, 6 tbl, 29 ex
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Authors
Dates
2018-10-16—Published
2014-12-22—Filed