XANTHOPHYLL COMPOSITION CONTAINING LUTEIN AND ZEXANTHIN WITH INCREASED BIOAVAILABILITY Russian patent published in 2025 - IPC A61K31/47 A61K31/07 A61K36/28 A61K36/81 A61K47/22 A61K47/44 A61P3/02 

FIELD: medicine; pharmaceutics.

SUBSTANCE: group of inventions relates to the pharmaceutical or nutraceutical industry, specifically to a xanthophyll composition. Pharmaceutical composition of xanthophylls containing: a) trans-R,R-lutein and trans-R,R-zeaxanthin in amount of 35 wt.% of the total weight of the composition; b) a carrier and/or carrier medium in amount of 51 wt.%, where said carrier and/or carrier medium is medium-chain triglyceride oil; c) a solubility enhancer in amount of 8 wt.%, where said solubility enhancer is mixture of 5 wt.% of olive oil, 1 wt.% of thyme oil and 2 wt.% of linseed oil; d) a flavouring agent in amount of 2 wt.%, where said flavouring agent is D-limonene; e) a bioavailability enhancing agent in amount of 2 wt.%, wherein said bioavailability enhancing agent is phosphatidylcholine; and f) an antioxidant in amount of 2 wt.%, where said antioxidant is mixed tocopherol; in which trans-R,R-lutein and trans-R,R-zeaxanthin are extracted from oil extracts of marigold and paprika, respectively, and are present in ratio of 5:1. Xanthophyll nutraceutical composition containing: a) trans-R,R-lutein and trans-R,R-zeaxanthin in amount of 35 wt.% of the total weight of the composition; b) a carrier and/or carrier medium in amount of 51 wt.%, where said carrier and/or carrier medium is medium-chain triglyceride oil; c) a solubility enhancer in amount of 8 wt.%, where said solubility enhancer is mixture of 5 wt.% of olive oil, 1 wt.% of thyme oil and 2 wt.% of linseed oil; d) a flavouring agent in amount of 2 wt.%, where said flavouring agent is D-limonene; e) a bioavailability enhancing agent in amount of 2 wt.%, wherein said bioavailability enhancing agent is phosphatidylcholine; and f) an antioxidant in amount of 2 wt.%, where said antioxidant is mixed tocopherol; in which trans-R,R-lutein and trans-R,R-zeaxanthin are extracted from oil extracts of marigold and paprika and are present in ratio of 5:1.

EFFECT: above-described xanthophyll compositions have high bioavailability.

20 cl, 8 dwg, 5 ex