2-DIETHYLAMINOETHYL-N-ALCYL-N,N′-DIETHYLISOTHIURONIUM DEHUDROBROMIDE CAPABLE OR IMPROVING RESISTANCE OF PERIPHERIC SECTION OF HEARING ANALYZER TO EFFECT OF SOUND LOAD AND TO OTOTOXIC EFFECT OF AMINOGLUCOSIDES Russian patent published in 1996 - IPC

Abstract SU 1098226 A1

FIELD: medicine. SUBSTANCE: no changes in urea, blood and also in internal organs were found during morphological investigations during subcutaneous injection of 50 mg/kg of agent in rats for 14 days. The use of agent of formula (I) makes it possible to improve resistance of peripheral section of hearing analyzer to the effect of aminoglucosides. The claimed invention discloses 2- diethylaminoethyl-N-alkyl-N,N′-diethylixothiuronium of formula: capable of improving resistance of peripheral section of hearing analyzer to the effect of sound load and to the ototoxic effect of aminoglucosides. EFFECT: improved properties of the title compound.

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SU 1 098 226 A1

Authors

Lin'Kov V.I.

Pastushenkov L.V.

Vinogradov V.M.

Rachinskij F.Ju.

Tomchin A.B.

Marysheva V.V.

Dates

1996-09-10Published

1982-07-05Filed