METHOD OF SYNTHESIS OF BIS-[(4-HYDROXYPHENYL)ALKYL]-SULFIDES Russian patent published in 1995 - IPC

FIELD: organic chemistry, organic sulfides. SUBSTANCE: products: bis-[(4-hydroxyphenyl)alkyl]-sulfides (HАS) of the general formula where R₁-R₂ tert.-butyl; R₃ hydrogen; n 1, 3; or R₁=R₂ tert. -butyl; R₃ methyl; n 2, or R₁ tert.-butyl; R₂-R₃ - hydrogen; n 1-2; or R₁ tert.-butyl; R₂ hydrogen; R₃ methyl; n 2. Synthesis of HAS is carried out by chlorination of corresponding (4-hydroxyphenyl)-alkanol (HPА) with compound (I) of the formula XCl₂, where X PCl, POCl, PCl₃ or SO in the medium of dimethylformamide (DMFA) at heating and treatment of synthesized chloride with anhydrous technical Na-sulfide in alcohol at boiling or with DMFA in water presence at concentration 10-15 wt.-% of total solvent quantity, at 70-90 C. If compound (I) PCl₃ or POCl₃ were used the process is carried out at the mole ratio HPA DMFA compound (1.8-2):2:1, at 90-100 C; if PCl₅ is used the molar ratio (2.7-3):(2-3):1, at 90-100 C; if SOCl₂ is used the molar ratio (0.8-1): 1:1, at 50-100 C. The yield of AHS is 74-84% as compared with 30-74% in the known method. Synthesized compounds can be used as stabilizing agents of polymeric materials. EFFECT: simplified process, increased yield and assortment of AHS. 4 cl, 3 tbl