1-(ISOFLAVONYL-7-OXYCARBONYLVINYL)-4- (ISOFLAVONYL-7-OXYCARBONYLMETHYLENOXY) BENZENE HAVING HYPOTENSIVE AND HYPOLIPIDEMIC ACTIVITIES Russian patent published in 1994 - IPC

Abstract SU 1531431 A1

FIELD: chemistry of heterocyclic compounds which can be used in medicine. SUBSTANCE: the synthesis of the desired compound is effected by reacting 7-hydroxyisoflavone with 4-carboxymethyleneoxycinnamic acid dichloride in toluene on boiling. The yield 70%, mp 282-283 C, the empirical formula: C41H26O9. The toxicity LD50 greater than 3000 mg/kg. The hypotensive activity of the new compound is by 2 times greater than that of theobromine, and the hypolipidemic activity of the new compound is by 1.5 times greater than that of cetamiphene. EFFECT: new compounds of said class which are more active within a wide range of activities. 2 tbl

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SU 1 531 431 A1

Authors

Luk'Janchikov М.S.

Кazakov А.L.

Ushakov V.В.

Vasilenko Ju.К.

Ivashev М.N.

Skul'Te I.V.

Dates

1994-09-30Published

1988-05-24Filed