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2 610 536

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IPC

G09B23/28(2006-01-01)

(21) (22)

Application

2015145039, 2015-10-20

(24)

Start date

2015-10-20

(22)

Actual filing date

2015-10-20

(45)

Published

2017-02-13

(72)

Inventor

Petrosyan Mariya AnatolevnaZhestkova Natalya VladimirovnaBalashova Natalya NikolaevnaPolyanskikh Lyudmila SergeevnaTumasova Zhanna NikolaevnaRazygraev Aleksej VyacheslavovichTral Tatyana GeorgievnaAjlamazyan Eduard Karpovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Nauchnoe Uchrezhdenie Institut Akusherstva, Ginekologii I Reproduktologii Imeni D.O. Otta"

METHOD FOR SIMULATING ACUTE LIVER DISEASE IN PREGNANT WOMEN Russian patent published in 2017 - IPC G09B23/28

Abstract RU 2610536 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to experimental pathophysiology, and can be used for simulating acute liver disease in pregnant women. For this purpose, pregnant female rats are administered intraperitoneally with tyloxapol water solution in dose of 300 mg/kg daily for four days from 15 to 18-th days of pregnancy.

EFFECT: method enables to obtain model, most close to clinical course of disease, at simplicity, efficiency in design and high survival rate in laboratory animals.

1 cl, 7 dwg

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RU 2 610 536 C1

Authors

Petrosyan Mariya Anatolevna

Zhestkova Natalya Vladimirovna

Balashova Natalya Nikolaevna

Polyanskikh Lyudmila Sergeevna

Tumasova Zhanna Nikolaevna

Razygraev Aleksej Vyacheslavovich

Tral Tatyana Georgievna

Ajlamazyan Eduard Karpovich

Dates

2017-02-13—Published

2015-10-20—Filed