1-(3,4-DIMETHOXYBENZYLOXY)-3-DIETHYLAMINO-2-PROPANOL HYDROCHLORIDE SHOWING UTERO-STIMULATING ACTIVITY Russian patent published in 1995 - IPC

Abstract SU 1804054 A1

FIELD: organic chemistry. SUBSTANCE: product: 1-(3,4-dimethoxybenzyloxy)-3-diethylamino-2-propanol hydrochloride: [3,4-(CH₃O)₂C₆H₄]CH₂OCH₂CH(OH)CH₂N(C₂H₅)₂·HCl,, empirical formula is C₁₆H₂₈ClNO₄ ,, yield is 84.3%. Reagent 1: 3,4-dimethoxybenzyl alcohol. Reagent 2: epichlorohydrin. Reaction conditions: at 45 C following by cooling and extraction of synthesized epoxide with ether, following treatment with diethylamine in the presence of water at boiling on the water bath for 7 h. Prepared 1-(3,4-dimethoxybenzyloxy)-3-diethylamino-2-propanol is treated with solution of HCl in ethanol. Synthesized product is used as a biologically active substance. EFFECT: improved method of synthesis. 1 tbl

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SU 1 804 054 A1

Authors

Zajtsev L.M.

Korotkij Ju.V.

Krasavtsev I.I.

Lozinskij M.O.

Klebanov B.M.

Dates

1995-03-27—Published

1990-10-10—Filed