1-ADAMANTYLETHYLOXY-3-MORPHOLINO-2-PROPANOL HYDROCHLORIDE SHOWING UTERO-STIMULATING ACTIVITY Russian patent published in 1995 - IPC

Abstract SU 1829354 A1

FIELD: organic chemistry. SUBSTANCE: product: 1-adamantylethyloxy-3-morpholinopropanol-2 hydrochloride, empirical formula is C19H34ClNO3,, yield is 52%, m. p. is 167-168 C. Reagent 1: 2-adamantylethanol. Reagent 2: epichlorohydrin. Reaction conditions: at 40 C in the presence of water, NaOH and triethylbenzylammonium chloride. Reagent 3: morpholine. Reaction condition: boiling in the presence of water. Reagent 4: 10% solution of HCl. Reaction conditions: in ethanol medium, at the room temperature. Synthesized compound is used in medicine. EFFECT: improved method of synthesis. 1 tbl

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SU 1 829 354 A1

Authors

Korotkij Ju.V.

Krasavtsev I.I.

Zajtsev L.M.

Lozinskij M.O.

Klebanov V.M.

Gorodetskova N.R.

Dates

1995-03-27Published

1991-06-17Filed