FIELD: organic chemistry. SUBSTANCE: product: 1-adamantylethyloxy-3-morpholinopropanol-2 hydrochloride, empirical formula is C19H34ClNO3,, yield is 52%, m. p. is 167-168 C. Reagent 1: 2-adamantylethanol. Reagent 2: epichlorohydrin. Reaction conditions: at 40 C in the presence of water, NaOH and triethylbenzylammonium chloride. Reagent 3: morpholine. Reaction condition: boiling in the presence of water. Reagent 4: 10% solution of HCl. Reaction conditions: in ethanol medium, at the room temperature. Synthesized compound is used in medicine. EFFECT: improved method of synthesis. 1 tbl
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Authors
Dates
1995-03-27—Published
1991-06-17—Filed