FIELD: biotechnology. SUBSTANCE: strain Bacillus megaterium VKPM B- -5818 - a producer of neutral metalloproteinase. Productivity of strain is 20-25 U/ml after 23-25 h of cultivation under intensive aeration at 30 C that is 2-3-times more as compared with parent strain-producer. Metalloproteinase producing by B. megaterium does not contain alkaline proteinase impurities and can be used for production of sweetener aspartam. EFFECT: enhanced production of enzyme.
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