5-{[3,5-BIS-(1,1-DIMETHYLETHYL)-4-HYDROXYPHENYL]- METHYL}-4-THIAZOLIDINONE SHOWING ANTIINFLAMMATORY AND ANTIARTHRITIS ACTIVITY Russian patent published in 1994 - IPC

Abstract RU 2014329 C1

FIELD: organic chemistry. SUBSTANCE: product: 5-{[3,5-bis-(1,1-dimethylethyl)-4-hydroxyphenyl] -methyl} -4-thiazolidinone, gross-formula is C₁₈H₂₇NO₂S, m.p. is 149-152 C. Reagent 1: 5-{[3,5-bis-(1,1-dimethylethyl)-4-hydroxyphenyl] -methylene}-2-thioxo-4-thiazolidinone. Reaction conditions: hydrogeneration of reagent 1 in the presence of palladium on carbon in solvent medium. Synthesized compound is used in medicine as antiinflammatory and antiarthritis drug. EFFECT: improved method of synthesis. 7 tbl

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RU 2 014 329 C1

Authors

Dzhill Ehnn Panetta[Us]

Dates

1994-06-15—Published

1992-06-19—Filed