FIELD: organic chemistry. SUBSTANCE: product: quadratic acid. Reagent 1: 3-acetoxy-2-cyclobutene-1-one or 1,3-cyclobutanedione. Reagent 2: base. Reaction conditions: halogenation at (-40)-(+40) C, hydrolysis at 50-150 C. Compound is used as drugs. EFFECT: improved method of synthesis. 7 cl
Authors
Dates
1994-08-15—Published
1991-02-25—Filed