DERIVATIVES OF DIAZEPINONE, MIXTURES OF THEIR ISOMERS AND THEIR SALTS Russian patent published in 1994 - IPC

FIELD: organic chemistry. SUBSTANCE: product: derivatives of diazepinone of formula (I), where B means one of two radicals a)-d) ; X - a group =CH or N when means residue of formula (a); R - unbranched or branched alkyl with 1-4 carbon atoms; R¹ and R² are similar or different and mean hydrogen atom, or alkyl with 1-4 carbon atoms; R₃ - H, Cl or methyl; R₄ and R₅ are similar or different and mean oxygen atom or alkyl with 1-4 carbon atoms. R₅ can means also halogen atom, m, p-1; o,n - 1 or 2, mixtures of their isomers or salts. Reagent 1: compound of formula (II). Reagent 2: compound of formula (III). Reaction conditions: preferably in the medium of solvent and at 40-100 C. Synthesized compounds are used in medicine. EFFECT: improved method of synthesis of compound indicated above. 3 cl, 3 tbl