METHOD FOR PREVENTING ATROPHY OF TESTICLE Russian patent published in 1994 - IPC

FIELD: medicine. SUBSTANCE: this method for preventing atrophy of testicle after rupture of tunica albuginea prescribes administering riboxine in daily dosage of 25 mg/kg immediately after injury has been received or 72 h prior to planned operation and during 30 days. Experiment involving operated testicle model has revealed the fact that disclosed method permits preserving normal amount of sex cells in ductules, fission of spermatogenic epithelium cells and normal completion of development cycle, formation of normal mature spermatozoa inclusive. At the same time, disclosed method favors preservation of endocrinic functionability of testis what can be judged by higher content of testosterone in blood plasma and greater index of relative percentage of testosterone and lutropine. Variations in all evaluated parameters of patients treated with riboxine and controls are certain with P not greater than 0.05. EFFECT: disclosed method is advantageous whenever there arise necessity in preserving male reproductive function in all cases intactness of tunica albuginea is disturbed. 1 tbl