FIELD: medicine, veterinary. SUBSTANCE: for increase of nonspecific resistance of organism in human and agricultural animals vaccines of preparation from nontoxigenic strain Corinebacterium diphtheriae 5047 are used. Preparation is used by cultivation of strain indicated on the liquid nutrient semisynthetic medium with preliminary growing of mother cultural fluid. Biomass grown is disintegrated, purified by differential centrifugation, sterilized and subjected for lyophilic drying. Method ensures to eliminate harmful by-side symptoms (intoxication, allergization, suppression, etc. ) in human and agricultural animals vaccination and in meet and milk food production. EFFECT: enhanced nonspecific resistance of organism. 7 cl, 2 tbl
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Authors
Dates
1994-09-15—Published
1992-05-25—Filed