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Application

4947577/04, 1991-06-21

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Actual filing date

1991-06-21

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Published

1994-10-15

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Inventor

Mikhajlitsyn F.S.Kovalenko F.P.Kozyreva N.P.Dzhabarova V.I.Lebedeva M.N.Lychko N.D.Uvarova N.A.Najdenova A.S.Bulanova T.E.

(73)

Holder

Institut Meditsinskoj Parazitologii I Tropicheskoj Meditsiny Im.E.I.Martsinovskogo

6-[4-(4-ALKYLPIPERAZINYL-1)PHENYLAMINO]-1,2,5-THIADIAZOLO[3,4- -H]QUINOLINES SHOWING ANTHELMINTIC ACTIVITY AT ALVEOLAR ECHINOCOCCOSIS AND HYMENOLEPIDOSIS Russian patent published in 1994 - IPC

Abstract RU 2021275 C1

FIELD: organic chemistry. SUBSTANCE: product: 6-[4-(4-methylpiperazinyl-1)phenylamino] -1,2,5-thiadiazolo[3,- 4-h]quinoline, empirical formula is C20H20H6S, yield is 90% , m. p. is 293-295 C. 6-[4-(4-Ethylpiperazinyl-1)phenylamino] -1,2,5-thiadiazolo-[3, - 4-h]quinoline, empirical formula is C21H22N6S, m. p. is 275-277 C. Compounds are synthesized by interaction of 6-chloro-1,2,5-thiadiazolo[3,4-h] quinoline with 4-(4-alkylpiperazinyl-1)aniline at boiling in hydrochloric acid. Synthesized compounds show anthelmintic action. EFFECT: improved method of synthesis. 3 tbl

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RU 2 021 275 C1

Authors

Mikhajlitsyn F.S.

Kovalenko F.P.

Kozyreva N.P.

Dzhabarova V.I.

Lebedeva M.N.

Lychko N.D.

Uvarova N.A.

Najdenova A.S.

Bulanova T.E.

Dates

1994-10-15—Published

1991-06-21—Filed

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