INHIBITOR OF HUMAN IMMUNODEFICIENCY VIRUS Russian patent published in 1994 - IPC

Abstract RU 2022011 C1

FIELD: medicine. SUBSTANCE: enzyme L-lysine-α-oxidase is used as an inhibitor of human immunodeficiency virus. Enzyme shows the following properties: it oxidizes L-lysine, L-arginine, L-phenylalanine, L-tyrosine and L-histidine, its mol. mass is 114 ± 39 kDa, isoelectric point at 4.25, pH optimum is 7.7 + 0.3, thermal stability: decrease activity at temperature above 60 C; inhibitors: Zn, Cu, Ba, Fe2+. EFFECT: enhanced properties of inhibitor. 2 tbl

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Authors

Berezov T.T.

Smirnova I.P.

Alekseev S.B.

Stepanova L.G.

Zverev V.V.

Gol'Tsov V.A.

Andzhaparidze O.G.

Vesa V.S.

Dates

1994-10-30Published

1990-04-09Filed