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2 103 274

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IPC

(21) (22)

Application

95118084/04, 1995-10-23

(22)

Actual filing date

1995-10-23

(45)

Published

1998-01-27

(72)

Inventor

Sen' V.D.Golubev V.A.Rukina N.A.Orlova T.G.Burlakova E.B.

(73)

Holder

Institut Biokhimicheskoj Fiziki RanInstitut Khimicheskoj Fiziki Chernogolovka Ran

NITROXYL DERIVATIVE OF AZIDO-DIDEOXYTHYMIDINE SHOWING ANTIVIRAL ACTIVITY Russian patent published in 1998 - IPC

Abstract RU 2103274 C1

FIELD: organic chemistry. SUBSTANCE: invention relates to new biologically active compounds - nitroxyl derivatives of azidothymidine of the general formula: where R¹ - radical containing nitroxyl group and R² = R¹ or H that show antiviral activity against RNA-containing viruses (human immunodefficiency virus and virus of vesicular stomatitis) and DNA-containing virus (cytomegalovirus). EFFECT: enhanced effectiveness of compounds. 5 tbl

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RU 2 103 274 C1

Authors

Sen' V.D.

Golubev V.A.

Rukina N.A.

Orlova T.G.

Burlakova E.B.

Dates

1998-01-27—Published

1995-10-23—Filed