METHOD FOR TREATING ENDOTOXICOSIS PATIENTS Russian patent published in 1994 - IPC

FIELD: medicine. SUBSTANCE: blood samples for toxicity tests are taken from patients with acute pathology of abdominal cavity organs accompanied by endotoxicosis. The central blood is obtained by puncturing the left subclavian vein and introducing the catheter to a length of 12-14 cm to reach the level of the nameless vein. The peripheral blood is obtained by puncturing the left cubital vein. Then the biological toxicity is determined by paramecium test. The obtained data are used to determine the toxicity difference (TD) between peripheral and central blood. At TD = 5.0 min and over, the medium grave state is diagnosed and closed lavage is carried out of the lymphatic system by perfusion of 200.0 isotonic physiological solution through a peripheral lymphatic vessel at the rate of 10-12 drops per minute. At TD - 3-4.9 min, heavy intoxication state is diagnosed and the lavage of the lymphatic system is carried out by the above-described method in combination with hemosorption. Blood for hemosorption is withdrawn from the catheter of the installed in advance into left subclavian vein to draw blood for toxicity test. The blood is passed through carbon sorbents SKN-6 in the amount of 1-2 l and reinfused into the ulnar vein by puncture. At TD = 0.5-2.9 min the extremely grave state is diagnosed and the lymphatic system is washed out by the above-described method in combination with lymphosorption. The latter is carried out by draining the thoracic duct. Toxic lymph is collected from the drain of the thoracic lymphatic duct and sorbed through sorbents SKN-6 then reinfused into the cubital vein. EFFECT: higher efficiency of treatment and shorter curing time achieved by making a biological blood toxicity test and undertaking a corresponding treatment based on its result; closed lavage of lymphatic system; lavage of lymphatic system and hemosorption, lavage of lymphatic system and lymphosorption.