FIELD: organic chemistry. SUBSTANCE: product - benzonitrile derivatives of the formula 4-CN-C6H4-O-(CH2)n-Y-CH(Z)-A where n = 1-2; Y - (CH2)m-group; m = 0-1, or CH(OH); Z - H, C1-C3-alkyl; A - -N(Ra)-(CH2)q-S(O)p-Rc-group or Ra′ Ra″ N(+)-(CH2)q-S(O)p-Rc where Ra, Ra′, Ra″ - hydroxy-C1-C5-alkyl and C1-C5-alkyl, R - Rc-C1-C4-alkyl which can be substituted with F. Synthesis is carried out under known conditions. Synthesized compounds are used in medicine. EFFECT: improved method of synthesis. 2 tbl
| Title |
Year |
Author |
Number |
| METHOD FOR OBTAINING BENZONITRILE DERIVATIVES |
0 |
- Knut Olle Seved Almgren
- Bernt Geran Duke Duker
- Gert Krister Strandlund
|
SU1836342A3 |
| METHOD FOR OBTAINING BENZONITRILE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS |
0 |
- Knut Olle Seved Almgren
- Bernt Geran Duke Duker
- Krister Gert Strandlund
|
SU1836343A3 |
| 4-(3-)ETHYL-(3-PROPYLOSULFINYL)-PROPYL) -AMINO-2-HYDROXYPROPOXY)BENZONITRILE AS STEREOISOMERS OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND METHOD FOR THEIR PRODUCTION |
1991 |
- Knut Olle Seved Almgren[Se]
- Chell' Jal'Mar Andersson[Se]
- Bernt Jeran Duke Duker[Se]
- Bu Robert Lamm[Se]
- Gert Krister Strandlund[Se]
|
RU2032663C1 |
| DERIVATIVES OF BENZIMIDAZOLE AND METHOD PRODUCTION THEREOF |
1987 |
- Tomas Ber'E Al'Minger[Se]
- Rol'F Aksel' Bergman[Se]
- Khans Bungord[Dk]
- Per Lennart Lindberg[Se]
- Gunnel Ehlizabet Sunden[Se]
|
RU2062778C1 |
| 4-FLUORO-2-{[ (4-METHOXY- 2-PYRIDINYL)METHYL]SULFINYL} -1H-BENZI- MIDAZOLE OR ITS PHYSIOLOGICALLY ACCEPTABLE SALTS, METHOD OF THEIR SYNTHESIS, AND PHARMACEUTICAL COMPOSITION OF 4-FLUORO -2-MERCAPTO-1H- BENZIMIDAZOLE AND 4-FLUORO -2-{[(4- METHOXY-2-PYRIDINYL) METHYL]THIO}-1H -BENZIMIDAZOLE |
1991 |
- Arne Ehlof Brehndstrem[Se]
- Per Lennart Lindberg[Se]
- Gunnel' Ehlisabet Sjunden[Se]
|
RU2042673C1 |
| 5-CHLORO-2-[(3,4-DIMETHOXY-2-PYRIDINYL)METHYL]SULFINYL)- 1H-BENZIMIDAZOLE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PROCESS FOR PREPARATION, PHARMACEUTICAL COMPOSITION AND 5-CHLORO-2-[(3,4-DIMETHOXY-2- PYRIDINYL)METHYL)THIO]-1H-BENZIMIDAZOLE |
1989 |
- Arne Uljuf Brendstrem[Se]
- Per Lennart Lindberg[Se]
- Karl Ingemar Starke[Se]
- Gunnel' Ehlisabet Sjunden[Se]
|
RU2070199C1 |
| AZABICYCLOOCTANE DERIVATIVE, PHARMACEUTICAL PREPARATIONS, METHOD FOR PROPHYLAXIS OR TREATMENT, METHODS FOR PREPARING COMPOUNDS, COMPOUNDS |
2000 |
- B'Ersne Magnus
- Ponten Frit'Of
- Strandlund Jert
- Svensson Peder
|
RU2262505C2 |
| METHOD OF OBTAINING DERIVATIVES OF AMINOPROPANOL |
0 |
- Bill Beniamin Rudolf Gustavsson
- Sven Anders Khedberg
- Bo Torsten Lundgren
|
SU1169533A3 |
| SOLID MEDICINAL FORM OF THE PROLONGED ACTION FOR CARDIOVASCULAR DISEASE TREATMENT |
1991 |
- Ulf Ehrik Iensson[Se]
- Ien Al'Bert S'Egren[Se]
|
RU2072840C1 |
| DERIVATIVES OF 3,3′-DITHIOBIS-(PROPIONIC ACID) OR THEIR STEREOISOMERS AND COMPOSITION SHOWING IMMUNOMODULATING ACTION |
1991 |
- Karl-Magnus Aleksander Andersson[Se]
- Sten Khokan Aksel' Bergstrand[Se]
- Anders Rudol'F Khall'Berg[Se]
- Bengt Uljuf Sehrnstrand[Se]
- Per Anders Sigvard Tunek[Se]
|
RU2041208C1 |
