Patenton — panteon of patents

(19)

RU

(11)

2 024 544

(13)

C1

(51)

IPC

(21) (22)

Application

4915765/04, 1991-03-04

(22)

Actual filing date

1991-03-04

(45)

Published

1994-12-15

(72)

Inventor

Tolstikov G.A.Baltina L.A.Pokrovskij A.G.Pljasunova O.A.Murinov Ju.I.

(73)

Holder

Institut Organicheskoj Khimii Ural'Skogo Otdelenija Ran

GLYCOPEPTIDE OF β-GLYCYRRHIZIC ACID WITH L-ASPARTIC ACID DIMETHYL ETHER SHOWING ANTI-AIDS-ACTIVITY Russian patent published in 1994 - IPC

Abstract RU 2024544 C1

FIELD: anti-AIDS-activ agent. SUBSTANCE: product: 3-O-[2-O- (N-b-D- glucopyranosyluranoyl -L-aspartic acid dimethyl ether)-N-b -D-glucopyranosyluranoyl -L-aspartic acid dimethyl ether]- (3b,20b)-11,30-dioxo-30 -(N-L-aspartic acid dimethyl ether)- 30-norolean-12-en, yield is 76.0%, value [α]2D

0 = +60 degree (c = 0.02 in methanol), empirical formula is C60H89N3O25. Reagent 1: β-glycyrrhizic acid. Reagent 2: L-aspartic acid dimethyl ether. Conditions: in the medium of dry dioxane in the presence of N-hydroxysuccineimide and N,N'-dicyclohexylcarbodiimide following by addition of triethylamine. EFFECT: improved method of synthesis. 1 tbl

Similar patents RU2024544C1

Title Year Author Number
β-GLYCYRRHIZIC ACID GLYCOPEPTIDE WITH L-GLUTAMIC ACID DIBUTYL ETHER SHOWING ANTI-AIDS-ACTIVITY 1991
  • Tolstikov G.A.
  • Baltina L.A.
  • Pokrovskij A.G.
  • Pljasunova O.A.
  • Sandakhchiev L.S.
 RU2024546C1
GLYCOPEPTIDE OF β-GLYCYRRHIZIC ACID WITH GLYCYL-L-VALINE METHYL ETHER SHOWING ANTI-AIDS-ACTIVITY 1991
  • Baltina L.A.
  • Pokrovskij A.G.
  • Pljasunova O.A.
  • Tolstikov G.A.
 RU2024542C1
β-GLYCYRRHIZIC ACID AMIDE WITH 6-AMINOURACIL SHOWING ANTI-AIDS-ACTIVITY 1991
  • Tolstikov G.A.
  • Baltina L.A.
  • Pokrovskij A.G.
  • Pljasunova O.A.
  • Murinov Ju.I.
  • Sandakhchiev L.S.
 RU2024545C1
β-GLYCYRRHIZIC ACID AMIDE WITH 6-AMINO-2-THIOURACIL SHOWING ANTI-AIDS-ACTIVITY 1991
  • Baltina L.A.
  • Pokrovskij A.G.
  • Pljasunova O.A.
  • Tolstikov G.A.
 RU2024547C1
β-GLYCYRRHIZIC ACID AMIDE WITH L-HISTIDINE METHYL ETHER SHOWING ANTI-AIDS-ACTIVITY 1991
  • Baltina L.A.
  • Pokrovskij A.G.
  • Pljasunova O.A.
  • Tolstikov G.A.
 RU2024543C1
GLYCYRRHIZIC ACID GLYCOPEPTIDE WITH S-BENZYL-L-CYSTEINE ELICITING ANTI-HIV ACTIVITY 2001
  • Kondratenko R.M.
  • Baltina L.A.
  • Pljasunova O.A.
  • Pokrovskij A.G.
  • Tolstikov G.A.
 RU2198177C2
GLYCYRRHIZIC ACID GLYCOPEPTIDE WITH GLYCYL-L-PHENYLALANINE ELICITING ANTI-HIV-1 ACTIVITY 2006
  • Baltina Lidija Ashrafovna
  • Pljasunova Ol'Ga Aleksandrovna
  • Baltina Lija Aleksandrovna
  • Pokrovskij Andrej Georgievich
  • Tolstikov Genrikh Aleksandrovich
 RU2315058C1
GLYCYRRHIZIC ACID AMIDE WITH 5-AMINOURACIL ELICITING ANTI-HIV-ACTIVITY 2001
  • Kondratenko R.M.
  • Baltina L.A.
  • Mustafina S.R.
  • Pljasunova O.A.
  • Pokrovskij A.G.
  • Tolstikov G.A.
 RU2199547C2
METHOD OF PREPARING CARBOXY-PROTECTED GLYCOPEPTIDES OF GLYCYRRHIZIC ACID 1992
  • Baltina L.A.
  • Ryzhova S.A.
  • Tolstikov G.A.
 RU2057139C1
AMIDE β GLYCIRRHIZIC ACID WITH PHENYLBORON ACID SHOWING ANTIINFLAMMATORY AND ANTIULCEROUS ACTIVITY 1991
  • Tolstikov G.A.
  • Baltina L.A.
  • Davydova V.A.
  • Jusupova F.G.
  • Zarudij F.A.
  • Monakov Ju.B.
  • Tolstikova T.G.
 RU2032694C1

RU 2 024 544 C1

Authors

Tolstikov G.A.

Baltina L.A.

Pokrovskij A.G.

Pljasunova O.A.

Murinov Ju.I.

Dates

1994-12-15—Published

1991-03-04—Filed

read Similar patents