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2 024 545

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Application

4916055/04, 1991-03-04

(22)

Actual filing date

1991-03-04

(45)

Published

1994-12-15

(72)

Inventor

Tolstikov G.A.Baltina L.A.Pokrovskij A.G.Pljasunova O.A.Murinov Ju.I.Sandakhchiev L.S.

(73)

Holder

Institut Organicheskoj Khimii Ural'Skogo Otdelenija Ran

β-GLYCYRRHIZIC ACID AMIDE WITH 6-AMINOURACIL SHOWING ANTI-AIDS-ACTIVITY Russian patent published in 1994 - IPC

Abstract RU 2024545 C1

FIELD: organic chemistry. SUBSTANCE: product: b-glycyrrhizic acid amide with 6-aminouracil: 3-O-[2-O- (b-D-glycopyranosyluranoyl) -b-D-glucopyranosyluranoyl] -(3b, 20b) -11,30- dioxo-30- (N-6- aminouracil) -30- norolean-12-en, empirical formula is C46H65N3O17, yield is 98.9%, m. p. is 261-264 C. Reagent 1: β-glycyrrhizic acid. Reagent 2: 6-aminouracil. Reaction conditions: in the medium of dry dimethylformamide, in the presence of N, N,N′-dicyclohexylcarbodiimide, at 50-60 C. EFFECT: improved method of synthesis. 1 tbl

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RU 2 024 545 C1

Authors

Tolstikov G.A.

Baltina L.A.

Pokrovskij A.G.

Pljasunova O.A.

Murinov Ju.I.

Sandakhchiev L.S.

Dates

1994-12-15—Published

1991-03-04—Filed

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