FIELD: organic chemistry. SUBSTANCE: product: antibacterial medicinal preparation containing derivative of quinoline carboxylic or naphthiridine carboxylic acids of the general formula (I) 
where X means carbon or nitrogen atom; R1 - hydrogen or fluorine atom; R2 - methyl, piperazine or methylpiperazine group, or R1 and R2 together form methylenedioxy-group, and derivative of tetracycline of the general formula (II) 
where R3 and R4 mean hydrogen atom, or R3 and R4 together form chemical bond taken at the ratio (1:0.5)-(1:50). Preparations show synergistic effect that allows to decrease dose and by-side action. EFFECT: increased effectiveness of preparations. 6 tbl
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