FIELD: organic chemistry. SUBSTANCE: products - phenylalkylamines of the general formula 
, where R1 - straight or branched (C2-C8)-alkyl, (C7-C10)-phenylalkyl, phenyl or (C3-C8)-cycloalkyl; R2 - 
-group, where R5 - H or (C1-C7)-alkyl, which can be substituted with halogen, hydroxyl, C1-C4-alkoxy- group or phenyl-C2-alkyl; R4 - hydrogen or 
-group instead of means cycloalkyl ring C3-C8. Condition that groups R1 and R2 contain in combination at least 5 carbon atoms. If R1 - ethyl, then R2 can not be isobutyl. Reagent 1: amine - C6H15-CH2CHR1NH2. Reagent 2: 
. Process is carried out in the presence of reducing agent - aluminium amalgam, gaseous hydrogen and metallic hydrogenation catalyst, alkaline metal boron hydride. Synthesized compounds are used in pharmaceutical industry. EFFECT: improved method of synthesis. 8 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| PROCESS FOR PREPARING PHENYLKYLAMINES OR SALTS OF THESE COMPOUNDS | 1990 |
|
RU2015960C1 |
| METHOD FOR SYNTHESIS OF PHENYLALKYLAMINES OR THEIRS PHARMACOLOGICALLY ACCEPTABLE SALTS | 0 |
|
SU1746882A3 |
| PHARMACEUTICAL COMPOSITION AND A METHOD OF ITS PREPARING, METHOD OF TREATMENT OF DISORDERS CAUSED BY NEURODEGENERATIVE PROCESSES | 1992 |
|
RU2125448C1 |
| ANTIMICROBIAL COMPOSITION | 1991 |
|
RU2030913C1 |
| METHOD OF SYNTHESIS OF QUINOLINECARBOXYLIC ACID DERIVATIVES | 1988 |
|
RU2014331C1 |
| METHOD OF SYNTHESIS OF QUINOLINE CARBOXYLIC ACID DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS | 1988 |
|
RU2049783C1 |
| METHOD OF SYNTHESIS OF PURE ISOFLAVONE DERIVATIVES | 1991 |
|
RU2036918C1 |
| TLATRATE OF 7-ISOPROPOXYISOFLAVONE AND CYCLODEXTRINE POLYMER SHOWING ACTIVITY AGAINST OSTEOPOROSIS AND OSTEOMALACIA | 1987 |
|
RU2022970C1 |
| PROCESS FOR PREPARING PHENYLGUANIDINE DERIVATIVES AND SULFONIC ACID DERIVATIVES AS INTERMEDIATES IN SYNTHESIS OF PHENYLGUANIDINE DERIVATIVES | 1991 |
|
RU2015963C1 |
| RACEMIC OR OPTICALLY ACTIVE DERIVATIVES OF ISOQUINOLINE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND A METHOD OF PHARMACEUTICAL COMPOSITION PREPARING | 1991 |
|
RU2090559C1 |
