FIELD: organic chemistry. SUBSTANCE: invention relates to new racemic or optically active compounds that are derivatives of isoquinoline of the general formula (I) given in description, their salts and hydrates, method of synthesis of these compounds and pharmaceutical compositions containing these compounds and method of preparing these compositions. Proposed compounds are antagonists of constrictive mediating agents (histamine, acetylcholine or serotonine). They show antiallergic and antiinflammatory effect. So, these compounds can be used in medicine for treatment, in part, bronchial asthma. EFFECT: improved method of synthesis, enhanced effectiveness. 34 cl, 23 tbl
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SU1047389A3 |
