FIELD: organic chemistry. SUBSTANCE: the product is (4-amino-2,6- dimethylphenylsulfonyl) mitromethane of the formula NH2-Ph(CH3)2-S(O)O-CH2-NO2; the empirical formula C9H12N2O4S; the yield is 73% ; mp 132-133 C. Product 2 is 4-acetamido-2,6-dimethylphenylsulfonyl) nitromethane of the formula CH3-C(O)-NH-Ph(CH3)2-S(O)O-CH2-NO2; the empirical formula C11H14N2O5S; the yield is 21% m p 179-180 C. The pharmaceutical composition based on compound 1. Compound 1 is prepared from compound 2 by hydrolysis of a strong acid and compound 2 is prepared by prior art methods. EFFECT: improved properties of the pharmaceutical composition. 4 cl
| Title | Year | Author | Number |
|---|---|---|---|
| PROCESS FOR PREPARING (4-AMINO)-2,6-DIMETHYLPHENYLSULFONYL NITROMETHANE | 0 |
|
SU1817776A3 |
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|
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|
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RU2045527C1 |
