FIELD: organic chemistry. SUBSTANCE: product: quinoline salt of the formula (I) where radicals R1, R2, R3 and R4 have corresponding meanings is used as an intermediate substance for synthesis of 1-alkyl-2-quinolone. Method of its synthesis involves interaction of compound of the formula (II) where radicals R2, R3 and R4 have corresponding meanings and a method of synthesis of 1-alkyl-2-quinolone of the formula (III) where radicals R2, R3 and R4 have corresponding meanings by interaction of quinoline derivative of the formula (IV) where radicals R and R have corresponding meanings with alkylating agent R1-X-X where R1 and X have corresponding meanings followed by oxidation of synthesized compound. Synthesized compounds were used as inhibitors of enzyme 5-lipoxigenase. EFFECT: improved method of synthesis. 6 cl
Title | Year | Author | Number |
---|---|---|---|
SUBSTITUTED ACYLAMINOBENZAMIDES HAVING FUNGICIDAL ACTIVITY AND PROCESS FOR PREPARING THEREOF | 1990 |
|
RU2034829C1 |
METHOD FOR PRODUCTION OF ACYL AMINOBENZAMIDE DERIVATIVES | 1991 |
|
RU2032662C1 |
PROPENOIC ACID DERIVATIVES SHOWING FUNGICIDIC ACTIVITY | 1989 |
|
RU2024496C1 |
1,3-DIOXANE DERIVATIVES OF ALKENOIC ACID OR THEIR PHARMACEUTICALLY ACCEPTABLE SALT | 1989 |
|
RU2040525C1 |
DERIVATIVES OF 1,3-DIOXANE ALKENOIC ACID | 1989 |
|
RU2045526C1 |
HETEROCYCLIC COMPOUND, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION | 1991 |
|
RU2070198C1 |
ARYL DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND METHODS OF THEIR SYNTHESIS | 1991 |
|
RU2067976C1 |
ACRYLIC ACID DERIVATIVES | 1991 |
|
RU2039044C1 |
HETEROCYCLIC COMPOUNDS POSSESSING HERBICIDE ACTIVITY, HERBICIDE COMPOSITION AND METHOD FOR CONTROL OF PARASITIC FLORA | 1991 |
|
RU2054003C1 |
METHOD OF SYNTHESIS OF BIPHENYLCARBONITRILES | 1991 |
|
RU2026285C1 |
Authors
Dates
1995-10-10—Published
1991-12-05—Filed