1,3(2,6-DIHYDROXY-4-THIAHEPTAMETHYLENE-6-METHYLURACIL HAVING IMMINOTROPIC AND ANTIINFLAMMATORY ACTIVITY Russian patent published in 1995 - IPC

Abstract RU 2034839 C1

FIELD: medicine. SUBSTANCE: 1,3-(2,6-dihydroxy-4- thiaheptamethylene)-6-methyluracil C11H16N2O4S, m.w. 272.32. Reagent 1: 1,3-bis(2′-hydroxy-3′-chloropropyl)-6- methyluracil prepared by treating 6-methyluracil with epichlorohydrine in the presence of a catalytic amount of potash in a DMFA solution at 70-80 C. Reagent 2: Na2S·9H2O. The process is carried out in DMFA at 140-150 C for 8 hours. EFFECT: improved properties of the title compound. 4 tbl

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RU 2 034 839 C1

Authors

Krivonogov V.P.

Tolstikov G.A.

Murinov Ju.I.

Zarudij F.S.

Lazareva D.N.

Davydova V.A.

Ismagilova A.F.

Sakhautdinova G.M.

Spirikhin L.V.

Abdrakhmanov I.B.

Krivonogova I.I.

Dates

1995-05-10Published

1992-10-05Filed