FIELD: medicine. SUBSTANCE: 1,3-(2,6-dihydroxy-4- thiaheptamethylene)-6-methyluracil C11H16N2O4S, m.w. 272.32. Reagent 1: 1,3-bis(2′-hydroxy-3′-chloropropyl)-6- methyluracil prepared by treating 6-methyluracil with epichlorohydrine in the presence of a catalytic amount of potash in a DMFA solution at 70-80 C. Reagent 2: Na2S·9H2O. The process is carried out in DMFA at 140-150 C for 8 hours. EFFECT: improved properties of the title compound. 4 tbl
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Authors
Dates
1995-05-10—Published
1992-10-05—Filed