FIELD: organic chemistry. SUBSTANCE: product - 1,3-bis-(isobutylthioethyl) -5-isobutylthioethylhydroxy -6-methyluracil, empirical formula is C23H42N2O3S3, yield is 42.18%. Reagent 1: 5-hydroxy-6-methyluracil. Reagent 2: β-chloroethylisobutylsulfide. Process conditions: in aqueous-spirituous solution in the presence of alkali. Synthesized compound is used in medicine as an immunotropic agent. EFFECT: improved method of synthesis. 3 tbl
Title | Year | Author | Number |
---|---|---|---|
1,3-BIS-(ISOBUTYLTHIOETHYL)-5-HYDROXY-6-METHYLURACIL SHOWING IMMUNOTROPIC ACTIVITY | 1991 |
|
RU2028296C1 |
1,3-BIS-(ISOBUTYLTHIOETHYL)-6-METHYLURACIL SHOWING IMMUNOTROPIC ACTIVITY | 1991 |
|
RU2028295C1 |
BIS- [2,4- DIOXO-6- METHYL -1,2,3,4- TETRAHYDROPYRIMIDINE -3- (5-MET- HYL-3-THIAHEXYL) -S] -CIS- DICHLOROPLATINUM SHOWING IMMUNOTROPIC ACTIVITY | 1991 |
|
RU2035467C1 |
(2,4- DIOXO -1,3-BIS - (5- METHYL -3- THIAHEXYL)-6-METHYL- 1,2,3,4- TETRAHYDROPYRIMIDINE -S,S) -CIS - DICHLOROPLATINUM SHOWING IMMUNOTROPIC ACTIVITY | 1991 |
|
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3-ISOBUTYLTHIOETHYL-6-METHYLURACIL SHOWING IMMUNOTROPIC ACTIVITY | 1991 |
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PYRIMIDINE ACYCLONUCLEOSIDES SHOWING IMMUNOTROPIC AND ANTIINFLAMMATORY ACTIVITY | 1992 |
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1,3(2,6-DIHYDROXY-4-THIAHEPTAMETHYLENE-6-METHYLURACIL HAVING IMMINOTROPIC AND ANTIINFLAMMATORY ACTIVITY | 1992 |
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RU2034839C1 |
5-HYDROXY-3,6-DIMETHYLURACIL SHOWING IMMUNOTROPIC ACTIVITY | 1991 |
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RU2035455C1 |
2-METHYL-4-AMINO-6-HYDROXYPYRIMIDINE AND METHODS OF ITS SYNTHESIS (VARIANTS) | 1998 |
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RU2165926C2 |
GLYCYRRHIZIC ACID DIGLYCOPEPTIDE WITH L-VALINE METHYL ESTER STIMULATING PRIMARY IMMUNE RESPONSE | 2003 |
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Authors
Dates
1995-01-27—Published
1991-03-11—Filed