FIELD: organic chemistry. SUBSTANCE: product: 3-isobutylthioethyl-6-methyluracil, empirical formula is C11H18N2O2S, yield is 40.9%, m. p. is 115-118 C. Reagent 1: 6-methyluracil. Reagent 2: β-chloroethylisobutylsulfide. Reaction conditions: in the mixture of water and benzene at 90-100 C. Synthesized compound is used as an immunotropic agent. EFFECT: improved method of synthesis.
Title | Year | Author | Number |
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BIS- [2,4- DIOXO-6- METHYL -1,2,3,4- TETRAHYDROPYRIMIDINE -3- (5-MET- HYL-3-THIAHEXYL) -S] -CIS- DICHLOROPLATINUM SHOWING IMMUNOTROPIC ACTIVITY | 1991 |
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RU2028295C1 |
(2,4- DIOXO -1,3-BIS - (5- METHYL -3- THIAHEXYL)-6-METHYL- 1,2,3,4- TETRAHYDROPYRIMIDINE -S,S) -CIS - DICHLOROPLATINUM SHOWING IMMUNOTROPIC ACTIVITY | 1991 |
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1,3(2,6-DIHYDROXY-4-THIAHEPTAMETHYLENE-6-METHYLURACIL HAVING IMMINOTROPIC AND ANTIINFLAMMATORY ACTIVITY | 1992 |
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PYRIMIDINE ACYCLONUCLEOSIDES SHOWING IMMUNOTROPIC AND ANTIINFLAMMATORY ACTIVITY | 1992 |
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2-METHYL-4-AMINO-6-HYDROXYPYRIMIDINE AND METHODS OF ITS SYNTHESIS (VARIANTS) | 1998 |
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RU2165926C2 |
2-[1-(1,1-DIOXOTHIETANYL-3) BENZIMIDAZOLYL-2-THIO] ACETIC ACID POTASSIUM SALT HAVING IMMUNOTROPIC ACTIVITY | 1996 |
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Authors
Dates
1995-05-20—Published
1991-03-11—Filed