FIELD: organic chemistry. SUBSTANCE: product: 5-[methyl,6-63H]-2,4-(1H, 3H)-pyrimidinedione. Thymine or 5-hydroxymethyluracil applied on the palladium catalyst (5% Pd per BaSO4) is treated with gaseous tritium at 145-200 C for 40 min. Synthesized compound is used in biochemistry. EFFECT: improved method of synthesis. 2 cl, 2 tbl
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METHOD OF TRITIUM LABELED COMPOUNDS SELECTED FROM CLASSES OF AMINO ACIDS, AMINES, AMINOSUGARS, SUGARS, PURINE AND PYRIMIDINE BASES AND NUCLEOSIDES, CARBOXYLIC ACIDS, NITROGEN-CONTAINING DERIVATIVES OF TETRAHYDROTHIOPHENE | 1987 |
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METHOD OF SYNTHESIS OF α-AMINO ACIDS LABELED WITH TRITIUM | 1986 |
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TRITIUM HIGH-LABELED DIMETHOMORPHOLINE AND METHOD OF PREPARATION THEREOF | 1998 |
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Authors
Dates
1995-05-20—Published
1992-03-30—Filed