METHOD OF SYNTHESIS OF PURINE BASES LABELED WITH TRITIUM Russian patent published in 1994 - IPC

Abstract SU 1545504 A3

FIELD: organic chemistry, biochemistry. SUBSTANCE: synthesis is carried out by isotope exchange with gaseous tritium at 170-210 C in the presence of catalyst Pd/BaSO4, on which corresponding purine base (for example, guanine, xanthine or hypoxanthine) is applied preliminary. Method is used for nucleic acid synthesis. EFFECT: enhanced molar activity of the end product (by 80-fold in the case of hypoxanthine). 5 tbl

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SU 1 545 504 A3

Authors

Mjasoedov N.F.

Sidorov G.V.

Voronkov A.L.

Kvjatkovskij Ju.G.

Ivan'Kova E.K.

Dates

1994-03-15Published

1986-10-27Filed